Launched in 2006, Uganda is the site of BRAC's largest and fastest scale-up in Africa. There are currently programmes operating in microfinance, small enterprises, agriculture, poultry and livestock, health, education, youth empowerment, adolescent livelihood, and the Karamoja initiative.

In particular, BRAC empowerment and livelihood for adolescents (ELA) programme is the largest youth empowerment platform in Uganda. The programme targets adolescent girls between the ages of 13 and 21, especially those who are out of school. The primary goal of the programme is to assist the girls to achieve greater economic and social empowerment and become agents of change in their families and communities.

With support from Women Win, BRAC started implementing the Goal Programme in 2014 with 1800 adolescent girls and young women.